Featured Papers

Chronic Liver Injury During Obstructive Sleep Apnea
Hepatology, Vol. 41, No. 6, 2005

Nightly Variability of Sleep-Disordered Breathing Measured Over 3 Nights
American Academy of Otolaryngology-Head and Neck Surgery, Volume 131 Number 6

Idiopathic edema is associated with obstructive sleep apnea in women
Sleep Medicine

Dynamic Upper Airway Soft-Tissue and Caliber Changes in Healthy Subjects and Snoring Patients
American Journal of Neuroradiology

Alternative Methods of Titrating Continuous Positive Airway Pressure
American Journal of Respiratory and Critical Care Medicine

Ventilatory Control and Airway Anatomy in Obstructive Sleep Apnea
American Journal of Respiratory and Critical Care Medicine

Polysomnography Performed in the Unattended Home Versus the Attended Laboratory Setting-Sleep Heart Health Study Methodology
SLEEP, Vol. 27, No. 3, 2004

Home diagnosis of the obstructive sleep apnoea/hypopnoea syndrome
Sleep Medicine Reviews, Vol. 7, No. 1, pp 53±59, 2003

Comparison of the NovaSom® QSG® , a New Sleep Apnea Home-Diagnostic System, and Polysomnography
James A. Reichert, Daniel A. Bloch, Elizabeth Cundiff, Bernhard A. Votteri
Sleep Medicine - May, 2003

Cardiovascular Effects of Continuous Positive Airway Pressure in Patients with Heart Failure and Obstructive Sleep Apnea
New England Journal of Medicine - Vol 348, No. 13 (Mar 27, 2003)

Menopausal Status and Sleep-disordered Breathing
American Journal of Respiratory and Critical Care Medicine - Vol 167, 2003

Sleep Apnea Affects Half of All Stroke Victims
Yasuyuki Kaneko, MD; Vlasta E. Hajek, MD; Vera Zivanovic, MD; Janet Raboud, PhD; and T. Douglas Bradley, MD
SLEEP - Vol. 26, No. 3, 2003

Obstructive Sleep Apnea
Flemons, WW
The New England Journal of Medicine - Vol. 347, No. 7 (August 15, 2002)

Increased Physician-Reported Sleep Apnea
The National Ambulatory Medical Care Survey
Andrew M. Namen, Donnie P. Dunagan, Alan Fleischer, Janine Tillett, Molly Barnett, W. Vaughn McCall, and Edward F. Haponik
Chest - Volume 121/Number 6 (June, 2002)

A Quantitative Assessment of Sleep Laboratory Activity in the United States - Update
Tachibana N, Ayas NT, White DP
Journal of Clinical Sleep Medicine (Jan 2005)

A Quantitative Assessment of Sleep Laboratory Activity in the United States
Tachibana N, Ayas NT, White DP
American Academy of Sleep Medicine Bulletin - Vol. 9, No. 2 (Spring 2002)

Epidemiology of Obstructive Sleep Apnea - A Population Health Perspective
Young T, Peppard P, Gottlieb D
American Journal of Respiratory Critical Care Medicine - Vol. 165, 2002

Scoring Variability Between Polysomnography Technologists in Different Sleep Laboratories
Collop, N
Sleep Medicine, Vol. 3 (1) (2002)

Clinical Validation of the Bedbugg™ in Detection of Obstructive Sleep Apnea
Claman D, Murr A, Trotter, K
Otolaryngology - Head and Neck Surgery, Vol. 125, No. 3 (September 2001)

Mild to Moderate Sleep Respiratory Events - One Negative Night May Not Be Enough
Le Bon O, Hoffman G, Tecco J, Staner L, Noseda A, Pelc I, Linkowski P
Chest/118/2/August, 2000

Unattended Home Diagnosis and Treatment of Obstructive Sleep Apnea Without Polysomnography
Veterans Administration
Archives of Family Medicine, Feb 9, 2000

Sleep Apnea and Cardiovascular Disease

Erectile dysfunction, obstructive sleep apnea syndrome and nasal CPAP treatment
Sleep Medicine

Treating Sleep Apnea in Heart Failure Patients
Journal of the American College of Cardiology

Inhibition of Awake Sympathetic Nerve Activity of Heart Failure Patients With Obstructive Sleep Apnea by Nocturnal Continuous Positive Airway Pressure
Journal of the American College of Cardiology

Long-Term Effects of Nasal Continuous Positive Airway Pressure Therapy on Cardiovascular Outcomes in Sleep Apnea Syndrome
Chest

Benefits of obstructive sleep apnoea treatment in coronary artery disease: a long-term follow-up study
European Heart Journal

Obstructive sleep apnoea is independently associated with an increased prevalence of metabolic syndrome
European Heart Journal

The Relationship Between Congestive Heart Failure, Sleep Apnea, and Mortality in Older Men
Chest; 124:1400–1405

Sleep disorders in patients with congestive heart failure
Curr Opin Pulm Med 9:453–458

Cardiovascular Effects of Continuous Positive Airway Pressure in Patients with Heart Failure and Obstructive Sleep Apnea
New England Journal of Medicine - Vol 348, No. 13 (Mar 27, 2003)

Hypertension and Obstructive Sleep Apnea
Current Hypertension Reports 2003, 5:380-385

Automatic Sleep Apnoea Detection using Measures of Amplitude and Heart Rate Variability from the Electrocardiogram
16th International Conference on Pattern Recognition

In vivo Platelet Activation Is Increased during Sleep in Patients with Obstructive Sleep Apnea Syndrome
Thomas Geiser, Florian Buck, Beat J. Meyer, Claudio Bassetti, André Haeberli, Matthias Gugger
Respiration - 2002; 69:229–234

Benefit of Atrial Pacing in Sleep Apnea Syndrome
Garrigue S, Bordier P, Jais P, et al.
The New England Journal of Medicine - Vol. 346, No. 6 (February 7, 2002)

Blood Pressure, Cardiac Structure and Severity of Obstructive Sleep Apnea in a Sleep Clinic Population
Kraiczi H, Peker Y, Caidahl K, Samuelsson A, Hedner J
Journal of Hypertension - Volume 19, No. 11 (November 2001)

Obstructive Sleep Apnea as a Risk Factor for Hypertension: Population Study
Lavie P, Herer P, Hoffstein V
BMJ - February 19, 2001, 320 (7233)

Sleep-disordered Breathing and Coronary Artery Disease
Mooe T, Franklin K, Holmstrom, Rabben T, Wikln
American Journal of Respiratory Critical Care Medicine - Vol 164, 2001

Cardiac Autonomic Control in Obstructive Sleep Apnea
Khoo M, Belozeroff V, Berry R, Sassoon C
American Journal of Respiratory Critical Care Medicine - Vol 164, 2001

Sleep-Disordered Breathing and Cardiovascular Disease - Cross-sectional results of the Sleep Heart Health Study
Shahar E, Whitney C, Redline C, Lee E, Newman A, Nieto F, O'Conner G, Boland L, Schwartz J, Samet J
For the Sleep Heart Health Study Research Group
American Journal of Respiratory Critical Care Medicine - Vol 163, 2001

Sleep-Related Breathing Disorder is an Independent Risk Factor for Uncontrolled Hypertension
Grote L, Hedner J, Peter JH
Journal of Hypertension (England) - Volume 18, No. 6 (June 2000)

Prospective Study of the Association Between Sleep-Disordered Breathing and Hypertension
Peppard P, Young T, Palta M, Skatrud J
New England Journal of Medicine, Vol. 342, No. 19 (May 11, 2000)

Sleep Apnea and Hypertension
Garcia-Rio F, Racionero MA, Pino JM, Martinez I, Ortuno F, Villasante C, Villamor J
Servicios de Neumologia, Hospital Universitario La Paz, Universidad Autonoma, Madrid, Spain. Chest - Volume 117, No. 5 (May 2000)

Association of Sleep Disordered Breathing, Sleep Apnea, and Hypertension in a Large Community Based Study
Nieto F, Young T, Lind B, Shahar E, Samet J, Redline S, D'Agostino R, Newman A, Lebowitz M, Pickering T.
For the Sleep Heart Health Study
JAMA - Vol. 283, No. 14 (April 12, 2000)

Respiratory Disturbance Index
An Independent Predictor of Mortality in Coronary Artery Disease
American Journal of Respiratory Critical Care Medicine - Vol. 162, 2000

The Cardiovascular Effects of Sleep-Disordered Breathing
Sutton, FD
The Journal for Respiratory Care Practitioners - April/May 1998

Occult Sleep Disordered Breathing in Stable Congestive Heart Failure
Javaheri, S, Parker T, Wexler L, Michaels S, Stanberry E, Nishyama H, Roselle G
Ann Intern Med. 1995;Vol. 122: 487-492

Sleep Apnea and Stroke

White Matter Disease and Sleep-Disordered Breathing After Acute Stroke
Neurology; 2003;61:959–963

Sleep-disordered breathing and stroke
Current Opinion Neurology, Feb 16, 2003

Sleep Apnea Affects Half of All Stroke Victims
Yasuyuki Kaneko, MD; Vlasta E. Hajek, MD; Vera Zivanovic, MD; Janet Raboud, PhD; and T. Douglas Bradley, MD
SLEEP - Vol. 26, No. 3, Jan 2003

Acute Ischemic Stroke and Sleep Apnea: First 3 Days
55th Annual Meeting - American Academy of Neurology
Massimiliano Siccoli, Dirk Hermann, Dagmar Schmid, Paul Summers, Thomas J rmann, Spyros Kollias, Claudio Bassetti

Cerebral Haemodynamics in Obstructive Sleep Apnoea and Cheyne-Stokes Respiration
Sleep Medicine Reviews, Dec 2002

Sleep-disordered breathing following acute stroke
Monthly Journal of the Association of Physicians 2002; 95

Carotid Wall Thickness in Patients with Obstructive Sleep Apnea
Stroke 2002; 33

Sleep Apnea Impairs Function in Stroke Patients
American Heart Association, Nov 21, 2001/p>

Sleep Apnea and Diabetes

Diabetes and Sleep Disturbances
Diabetes Care - 26; 2003

Obstructive Sleep Apnea: Its Relevance in the Care of Diabetic Patients
Clinical Diabetes - 24; March 2002

Snoring Linked to Diabetes, Irrespective of Weight
American Journal of Epidemiology, March 4, 2002

Diabetes and Sleep Apnea
Strohl KP
Sleep 1996 Dec; 19 (10 Suppl):S225-8

Sleep Apnea and Obesity

Predicting Sleep Apnea and Excessive Day Sleepiness in the Severely Obese
Chest / 123 /4 /April, 2003

Low Sleep Quality and Daytime Sleepiness in Obese Patients Without Obstructive Sleep Apnoea Syndrome
Journal of Internal Medicine 2003; 253: 536–543

Obesity and Weight Loss in Obstructive Sleep Apnea
Sleep, 19(2), 1996

Sleep Apnea and Women

Women's Sleep Disorders May Be Tied to Hormones
Stanford Sleep Disorders Center, Feb 2003

Menopausal Status and Sleep-disordered Breathing
American Journal of Respiratory and Critical Care Medicine - Vol 167, Jan 2003

Hormone Replacement Therapy and Sleep-disordered Breathing
American Journal of Respiratory and Critical Care Medicine - Vol 167, Jan 2003

Effect of testosterone on the apneic threshold in women during NREM sleep
Journal of Applied Physiology - Vol 94, Jan 2003

Primary Predictors of OSAS Differ in Men and Women
American Academy of Otolaryngology Head and Neck Surgery, Sept 21, 2002

Sleep Apnea and Other Diseases

Predictors of symptoms of anxiety and depression in obstructive sleep apnea
Sleep Medicine

Investigation into sleep disturbance of patients suffering from cluster headache
Cephalalgia

Endocrine effects of nasal continuous positive airway pressure in male patients with obstructive sleep apnoea
Journal of Internal Medicine, 254: 447–454

Gastroesophageal Reflux Common in Patients With Sleep Apnea Rather Than Snorers Without Sleep Apnea
Chest / 124 /2 / August, 2003

Symptomatic Gastroesophageal Reflux in Subjects With a Breathing Sleep Disorder
Chest / 121 /6 / June, 2002

Relation of Measures of Sleep-Disordered Breathing to Neuropsychological Functioning
Adams N, Strauss M, Schluchter M, Redline S
American Journal of Respiratory Critical Care Medicine - Vol. 163, 2001

Improvement of Sleep Apnea in Patients with Chronic Renal Failure Who Undergo Nocturnal Hemodialysis
Hanly PJ, Pierrator A
The New England Journal of Medicine, Vol. 344, No. 2, Jan 2001

Obstructive Sleep Apnea is Common in Medically Refractory Epilepsy Patients
Malow B, Levy K, Maturen K, Bowes R
Neurology 55 - October 2000 (1 of 2)

Sleep Disordered Breathing in Patients with Cluster Headaches
Chervin RD, Zallek S, Lin X, Hall JM, Sharma N, Hedger KM
Neurology 54 - June 2000 (2 of 2)

Sleep Apnea and Motor Vehicle Accidents

Serious Motor Vehicle Crashes: The Cost of Untreated Sleep Apnea
Findley LJ, Suratt PM
Thorax - Volume 56, No. 7, July 2001

The Road to Danger: The Comparative Risks of Driving While Sleepy
Powell N, Shechtman K, Riley R, Li K, R. Troell, Guilleminault C
Laryngoscope 111: May 2001

Reduction in Motor Vehicle Collisions Following Treatment of Sleep Apnea with Nasal CPAP
George CFP
Thorax - 2001, Vol. 56, March 2001

Sleepiness-Related Accidents in Sleep Apnea Patients
Horstman S, Hess CW, Bassetti C, Switzerland B
Sleep - Volume 23, No. 3, March 2000

The Association Between Sleep Apnea and the Risk of Traffic Accidents
Teran-Santos J, Jimenez-Gomez A, Cordero-Guevara J, and the cooperative group Burgos-Santander
New England Journal of Medicine - Vol. 340, No. 11 (March 18, 1999)

Sleepiness, Driving and Accidents - Sleep Disordered Breathing and Motor Vehicle Accidents in a Population-Based Sample of Employed Adults
Young T, Blustein J, Finn L, Palta M
Sleep - Vol. 20, No. 8, April 1997

Sleep Apnea and CPAP Therapy

Long-term effects of nasal continuous positive airway pressure therapy on cardiovascular outcomes in sleep apnea syndrome
Chest

I Can’t Stand CPAP. What Else Can You Do for Me?
Journal of Clinical Sleep Medicine

A Comparison of Auto-Adjusting CPAP, Bilevel CPAP, and Standard CPAP Therapy in Patients with REM Related Obstsructive Sleep Apnea
55th Annual Meeting - American Academy of Neurology
Timothy J. Walter, Gautam Samadder, Brandon Strausbaugh, Lisa Brant

Nonattended home automated continuous positive airway pressure titration: Comparison with polysomnography
B. Tucker Woodson, MD, Adrian Saurejan, MD, Laura T. Brusky, MD, Joseph K. Han, MD
Otolaryngology--Head and Neck Surgery, March 2003

Efficacy and Cost of Home-Initiated Auto-nCPAP versus Conventional nCPAP
Carole Planès MD, PhD; Marie-Pia D'Ortho MD, PhD; Arlette Foucher MD; Malika Berkani MD; Karl Leroux; Mohamed Essalhi MD; Christophe Delclaux MD, PhD; Maria-Antonia Quera-Salva MD, PhD; Frédéric Lofaso MD, PhD
Sleep, Vol. 26, No. 2, 2003

Comparison between Automatic and Fixed Positive Airway Pressure Therapy in the Home
Clifford A. Massie, Nigel McArdle, Robert W. Hart, Wolfgang W. Schmidt-Nowara, Alan Lankford, David W. Hudgel, Nancy Gordon, and Neil J. Douglas
American Journal of Respiratory and Critical Care Medicine, Vol 167, 2003

Can Patients with Obstructive Sleep Apnea Titrate Their Own Continuous Positive Airway Pressure?
Michael F. Fitzpatrick, Christi E. D. Alloway, Tracy M. Wakeford, Alistair W. MacLean, Peter W. Munt, and Andrew G. Day
American Journal of Respiratory and Critical Care Medicine, Vol 167, 2003

Psychologic Correlates of Compliance with Continuous Positive Airway Pressure
Carl J.Stepnowsky,Jr,PhD; Wayne A.Bardwell, PhD; Polly J.Moore,PhD; Sonia Ancoli-Israel,PhD; Joel E.Dimsdale,MD
Sleep, Vol. 25, No. 7, 2002

Long-term Compliance Rates to Continuous Positive Airway Pressure in Obstructive Sleep Apnea: A Population Base Study
Sin D, Mayers I, Man G, et al.
Chest 2002, Vol. 121

Randomized Placebo-controlled Trial of Continuous Positive Airway Pressure on Blood Pressure in the Sleep Apnea-Hypopnea Syndrome
Faccenda JF, MacKay Thomas, Boon N, Douglas NJ
American Journal of Respiratory Critical Care Medicine - Vol. 163, 2001

Accuracy of an Unattended Home CPAP Titration in the Treatment of Obstructive Sleep Apnea
Unité de Recherche, Centre de Pneumologie, Hôpital et Université Laval, Québec, Canada
American Journal of Respiratory Critical Care Medicine - Vol 162. pp 94-97, 2000

Long-term Randomized, Cross-over comparison of Auto-titrating and Standard Nasal Continuous Airway Pressure
Hudgel D, Fung C
Sleep - Vol. 23, No. 5. 2000

Treatment with Nasal CPAP Decreases Automobile Accidents in Patients with Sleep Apnea
Findley L, Smith C, Hooper J, Dineen M, Suratt
American Journal of Respiratory Critical Care Medicine - Vol. 161, 2000

Cardiac Rhythm Disturbances in the Obstructive Sleep Apnea Syndrome - Effects of Nasal Continuous Positive Airway Pressure Therapy
Harbison J, O'Reilly P, McNicholas T
Chest - Volume 118, No. 3 (September 2000)

Cost Justification for Diagnosis and Treatment of Obstructive Sleep Apnea
Sleep

Reduced Hospitalization with Cardiovascular and Pulmonary Disease in Obstructive Sleep Apnea Patients on Nasal CPAP Treatment
Peker Y, Hedner J, Johansson A, Bende M
Sleep - Vol. 20, No. 8, 1997

Quality Adjusted Life Years Added by Treatment of Obstructive Sleep Apnea
Tousignant P, Cosio M, Levy R, Groome P
Sleep, 17(1): 52-60, 1994

Sleep Apnea & Titration

Relative accuracy of algorithm-based prescription of nasal CPAP in OSA
Respiratory Medicine, February 2004

Sleep Apnea & Pulse Oximetry

Utility of Oxygen Saturation and Heart Rate Spectral Analysis Obtained From Pulse Oximetric Recordings in the Diagnosis of Sleep Apnea Syndrome
Chest, Vol. 123, No. 5 2003

Cost-Related Articles

Cost Justification for Diagnosis and Treatment of Obstructive Sleep Apnea
American Academy of Sleep Medicine
Sleep, Vol. 23, No. 8, 2000

The Medical Cost of Undiagnosed Sleep Apnea
Kapur V, Blough D, Sandblom R, Hert R, deMaine J, Sullivan S, Psaty B
Sleep, Vol. 22, No. 6, 1999

Health Care Utilization in Males with Obstructive Sleep Apnea Syndrome Two Years After Diagnosis and Treatment
Bahammam A, Delaive K, Ronald J, Manfreda J, Roos L, Kryger M
Sleep, Vol. 22, No. 6, 1999

Health Care Utilization in the 10 Years Prior to Diagnosis in Obstructive Sleep Apnea Syndrome Patients
Ronald J, Delaive K, Roos L, Manfreda J, Kreyger M
Sleep - Vol. 22, No. 2, 1999

Utilization of Health Care Services in Patients with Severe Obstructive Sleep Apnea
Kryger M, Roos L, Delaive K, Walld R, Horrocks J
Sleep - Vol. 29, No. 9, 1996

Prevalence of Sleep Apnea

Sleep problems and the risk for sleep disorders in an outpatient veteran population
Sleep and Breathing

Low Rates of Recognition of Sleep Disorders in Primary Care: Comparison of a Community-based versus Clinical Academic Setting
Rosen R, Zozula R, Jahn E, Carson J
Sleep Medicine 2 (2001) 47-55

Obstructive Sleep Apnea-Hypopnea and Related Clinical Features in a Population-based Sample of Subjects Aged 30 to 70 Yr.
Duran J, Esnaola S, Rubio R, Iztueta A
American Journal of Respiratory Critical Care Medicine, Vol. 163, 2001

The Occurrence of Sleep-Disordered Breathing Among Middle-Aged Adults
Young T, Palta M, Dempsey P, Skatrud J, Weber S, Badr S
New England Journal of Medicine - Vol. 328 (April 29, 1993)

Pediatrics

Sleep disorders in children
Curr Opin Pulm Med 9:471–476

Sleep Characteristics Following Adenotonsillectomy in Children With Obstructive Sleep Apnea Syndrome
Chest / 124 /3 / September, 2003

Additional Articles

History of the Development of Sleep Medicine in the United States
Journal of Clinical Sleep Medicine

Correlation Between Otorhinolaryngologic Evaluation and Severity of Obstructive Sleep Apnea Syndrome in Snorers
Archives Otolaryngology Head and Neck Surgery

Evaluation of the Accuracy of SNAP Technology Sleep Sonography in Detecting Obstructive Sleep Apnea in Adults Compared to Standard Polysomnography
Chest 2004 125: 879-885

Role of portable sleep studies for diagnosis of obstructive sleep apnea
Curr Opin Pulm Med 9:465–470

Home Healthcare Electronics: Consumers Are Ready, Willing and Able
Charles Roussel, Paul F. Nunes
Accenture, January 2003

The Association of Sleep-Disordered Breathing and Sleep Symptoms with Quality of Life in Sleep Heart Health Study
Baldwin C, Griffith K, Nieto F, O'Conner G, Walslben J, Redline S
Sleep - Vol. 24, No. 1, 2001

Unattended Home Diagnosis and Treatment of Obstructive Sleep Apnea Without Polysomnography
Fletcher E, Stich J, Yang K
Archives of Family Medicine - Volume 9, February 2000

Sleep-disordered Breathing and Self-Reported General Health Status in the Wisconsin Sleep Cohort Study
Finn L, Young T, Palta M, Fryback D
Sleep, Vol. 21, No. 7, 1998

The Sleep Heart Health Study: Design, Rationale, and Methods
Quan S, Howard B, Iber C, Kiley J, Nieto F, O'Conner T, Rapoport D, Redline S, Robbins J, Samet J, Wahl P
Sleep - Vol. 20, No. 12, 1997